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The Realities Behind The Human Growth Hormone
What is human growth hormone (HGH) and how does it occur in children and adults? What are the causes, theories and mechanisms behind HGH?
Human growth hormone (HGH) is produced by the pituitary gland that is needed for growth. It plays a vital role in how the body uses food for metabolism. The amount of growth hormone in the blood changes at daytime because it is affected by so many factors like sleep, exercise, emotional stress, and diet.
HGH in childhood
Gigantism is the result of excessive HGH during childhood while dwarfism is caused by a small amount of HGH. This condition is treatable if diagnosed at an early age or at birth, through the so-called new born screening (NBS). The said technique can help in identifying the child's abnormality, in the future.
HGH in adults
In adults, excessive HGH is due to a non-cancerous tumor of the pituitary gland called adenoma. This excessive HGH can cause enlarging of the bones in the face, jaw, hands, and feet. This is seen to be extraordinary compared to the normal size.
Causes of HGH
Human growth hormones can be caused by the release of other substances that affect both growth and energy. One of the most affected aspects by HGH is the insulin-like growth factor (IGF-1). If there is an excessive HGH, the insulin growth factor 1 is also high.
HGH theories
There are two theories on how HGH affects the growth of an individual. The first theory is the Dual Effector Theory, and the second is called Somatomedin Hypothesis. The Dual Effector Theory states that HGH has an anabolic effect on the body tissues. The Somatomedin Hypothesis, on the other hand says that HGH strengthens its growth by promoting the effect through IGF-1.
The main difference between these two theories is that the first theory says that HGH does not necessarily need IGF-1 to work, while the second insists that it does. In further studies, some experts say that both of these theories are correct. The only thing that this two cannot bring forth together is that, somatemodin hypothesis focuses on the importance of IGF-1, while the dual effector theory insists that though IGF-1 is an active hormone thus it does not have to come from the blood. It can be produced on location by the cells that use it.
Mechanisms of HGH
The three main mechanisms by which the HGH makes things grow through the combination of the dual effector theory and the somatemodin hypotheses are:
• The effect of human growth hormone in bone formation and body organs growth are transmitted by the endocrine action of IGF-1.
• Human growth hormone regulates the activity of IGF-1 by increasing the production of binding proteins that increase the life span of IGF-1 from minutes to hours.
• Human growth hormone may influence the activity of IGF-1 on an autocrine or paracline level. Autocrine means that a hormone has an effect on the cell that produced it, while paracline means to have an effect on the cell next to it.
Human growth hormone is something that the body synthesizes. You do not have to take products just to boost your HGH levels. You can boost your HGH levels naturally if you are going to change your lifestyle.
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